Monday, February 18, 2013

GI3 Case A Answers

As the pathologist you receive the following specimen from autopsy.

Diagnose the disease process using the following photo:

Pancreatic Adenocarcinoma

Here is a list of some of the causes of the disease process you've just diagnosed. Name the most common cause.

Diabetes Mellitus.
Hereditary Pancreatitis
High Saturated Fat Diet
Smoking
Chronic Pancreatitis

Even before you see the histological slide that your 4th year medical student labeled their findings for you, you already came up with a litany of questions to pimp your student on this disease. You look at the following slide, and then you start asking her questions.


What do you think the most common clinical presentation is for this disease process? Use the following photo to help you and name your clinical finding.



Your patient mostly likely complained of epigastric pain with associated unintentional weight loss with a new presentation of jaundice. Using the above photo; scleral icterus.

Describe the unifying pathophysiolgy behind these three common presentations of this disease process and its relation to the most common location of this disease.

Jaundice
Light Colored Stools
Palpable Gallbladder (Courvoisier's Sign)

Common bile duct obstruction (carcinoma of the head of the pancreas)

Name these physical findings and the cancers associated with it.
Virchow's Node
Pancreatic and Stomach Cancer

Sister Mary Joseph's Sign
Pancreatic and Stomach Cancer

What is the gold standard tumor marker associated with this disease?

CA19-9

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