Monday, October 8, 2012

Block 2 Case 6 - Vascular



A 47 year old man patient presents to the ER with hematuria and hemoptysis with a history of chronic sinusitis. His UA shows elevated creatinine/BUN in addition to elevated protein. Additionally, he has noted tha his vision is worse and he has very poor circulation in his fingers.

What is the above immunofluorescence pattern associated with? What enzyme is responsible for the reaction? 

What is the most likely diagnosis?

Describe the following pathology specimens obtained from the patient:




What forms of vasculitis are associated with ANCAs - name 3 and give a brief description of each.



When a biopsy of the kidney is obtained it shows the following - what form of glomerulonephritis is this?

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