Mr. Thompson is a 75
year old African American gentleman who presents to your office with bone pain
and fatigue. He has been getting sick a lot lately which he insists is quite
unusual. His lab results show that he
has anemia and hypercalcemia. It is also suggestive of kidney damage (elevated BUN/Cr).
A bone marrow biopsy/aspirate are shown below:
What is the predominant cell type seen above? What type of neoplasm is this?
Why is there hypercalcemia?
What is monoclonal gammopathy? What type would you expect to see?
Do you expect to see a hyperviscosity syndrome like you do in Waldenstrom macroglobulinemia?
How is this illness similar/different from Waldenstroms?
Why does he have kidney problems?
Where are lytic lesions typically found?
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