A 65 year old female presents to the office with complaints
of fatigue, petechiae and sternal tenderness. Upon physical exam you note HSM
and pallor. Her lab work shows she has anemia
and a highly elevated WBC count.
- What is causing the increase in WBCs?
- Why does she have petechiae?
- Would you expect the LAP score to be increased, decreased, or show no change?
- Describe the bone marrow core / aspirate
- What do you think she has?
- What translocation is typically associated with the form of leukemia?
- What can we use to treat this type of leukemia and what does it target?
- What is the patient at risk for if we do not treat her?
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